The Lab

WORK IN THE HELAINE LAB IS FOCUSED ON THE HETEROGENOUS BEHAVIOUR OF SALMONELLA DURING INFECTION. INVESTIGATIONS ARE AIMED AT ELUCIDATING HOW BACTERIA ENTER INTO, SURVIVE DURING AND EXIT A NON-GROWING PERSISTER STATE WHICH ALLOWS THEM TO EVADE BOTH THE TREATMENT OF ANTIBIOTICS AND THE HOST IMMUNE RESPONSES.

THE HELAINE GROUP WAS INITIALLY FORMED AT THE CENTRE FOR MOLECULAR BACTERIOLOGY AND INFECTION AT IMPERIAL COLLEGE LONDON IN THE UK WHERE IT REMAINED FOR 6 YEARS. RECENTLY THE GROUP HAS MOVED TO HARVARD MEDICAL SCHOOL IN BOSTON, USA.